Argentine forward Angel Correa and Spanish midfielder Marcos Llorente scored doubles Atletico, and Belgian midfielder Yannnick Carrasco also stood out.
After 31 games, Atletico have 70 points and are on top of the championship table. Real Madrid, which played one match less, have 66 points and are in second place, followed by Eibar with 23 points.
Spanish football championship, 33rd round
Angel Correa, 42, 44, Yannick Carrasco, 49, Marcos Llorente, 53, 68